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Quantification of Process Induced Disorder in Milled

An oscillatory ball mill Mixer Mill MM301 Retsch & Co Germany was used for cryo milling as follows 1 g of indomethacin was placed into a 25 mL milling jar and milled with two 12 mm balls for 120 minutes

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Effect of milling conditions on the solid-state conversion

Both ranitidine hydrochloride form 1 and form 2 were milled separately in an oscillatory ball mill Mixer Mill MM301 Retsch & Co Germany at 30 Hz A 1 g powder sample was placed in a 25 mL volume stainless steel milling jar containing two 12 mm diameter stainless steel balls

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Milling was carried out using an oscillatory ball mill Mixer Mill MM301 Retsch & Co Germany In cryo-milling the milling jars were In cryo-milling the milling jars were Ball Mills Pauley Equipment Northern Ireland UK The Fritsch P23 micro mill has been specifically designed for the milling of small quantities of material <5ml

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Physical characterization and stability of amorphous

The drugs were co-milled using an oscillatory ball mill Mixer Mill MM301 Retsch & Co Germany A total of 1 g of powder at varying ratios indomethacin to ranitidine hydrochloride ratio 2 1 1 1 1 2 w/w was used for each milling

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